CT of Depression in Private Practice is as Effective as in Research Trials

Persons, J. B., Bostrom, A. & Bertagnolli, A. (1999). Results of Randomized Controlled Trials of Cognitive Therapy for Depression Generalize to Private Practice. Cognitive Therapy and Research, 23, 535-548.

ABSTRACT - We compared outcomes of 45 depressed patients treated in private practice with cognitive therapy or with cognitive therapy plus pharmacotherapy to outcomes of patients receiving those treatments in two randomized controlled trials. Private practice and research samples differed considerably, with private practice practice patients having more medical and psychiatric co-morbidities and a greater range of initial depression severity. Treatment in private practice and research settings also differed considerably, with private practice treatment conducted in a more flexible manner usind an idiographic, formulation-driven approach. As predicted, private practice patients showed statistically significant reductions in depressive symptomatology over the course of treatment, and at posttreatment, Beck Depression Inventory (BDI) scores of patients treated in private practice and research settings were not statistically significantly different. Clinical significance of outcomes was also comparable in the clinical and research samples. Of the variables measuring demographic, illness, and treatment factors, only pretreatment BDI score predicted posttreatment BDI score in the private practice sample.

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